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src-selective kinase inhibitor pp1  (Merck KGaA)

 
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    Merck KGaA src-selective kinase inhibitor pp1
    Src Selective Kinase Inhibitor Pp1, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/src-selective kinase inhibitor pp1/product/Merck KGaA
    Average 90 stars, based on 1 article reviews
    src-selective kinase inhibitor pp1 - by Bioz Stars, 2026-03
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    Image Search Results


    UM1 (06-12) and Mel270 treatment with Src inhibitors (PP1/PP2) identified eight substrates with a significant reduction in phosphorylation ( A ). The inhibition of EFS peptide phosphorylation by genetic (Src siRNA) and pharmacological means (PP1) in cell line Mel270, and PP1 treatment of cell lysates of UM (UM1) and metastasis tissue (MET3) ( B ).

    Journal: British Journal of Cancer

    Article Title: Episodic Src activation in uveal melanoma revealed by kinase activity profiling

    doi: 10.1038/sj.bjc.6605172

    Figure Lengend Snippet: UM1 (06-12) and Mel270 treatment with Src inhibitors (PP1/PP2) identified eight substrates with a significant reduction in phosphorylation ( A ). The inhibition of EFS peptide phosphorylation by genetic (Src siRNA) and pharmacological means (PP1) in cell line Mel270, and PP1 treatment of cell lysates of UM (UM1) and metastasis tissue (MET3) ( B ).

    Article Snippet: Blocking experiments were carried out with Src family-selective tyrosine kinase inhibitors, PP1, PP2 (Biomol International, LP, of Plymouth Meeting, PA, USA) and PP3 (the inactive analogue, Calbiochem), at an end concentration of 10 μ M in line with a large body of literature.

    Techniques: Phospho-proteomics, Inhibition